ABSTRACT
ABSTRACT: Endometrial carcinoma is a very rare cause of cutaneous metastasis.The most frequent presentations of cutaneous metastasis are fast developing nodules or tumors, which are evi-dence of widespread dissemination in such patients.We report a case of scalp metastasis from an endometrial adenocarcinoma with a fatal prognosis. (AU)
RESUMO: O carcinoma endometrial é uma causa rara de metástases cutâneas.A apresentação mais frequente de metástases cutâneas são nódulos ou tumores de rápido desenvolvimento, que evidenciam uma disseminação generalizada nesses pacientes.Relatamos um caso de metástase no couro cabeludo de um adenocarcinoma endometrial com prognóstico fatal. (AU)
Subject(s)
Humans , Aged , Prognosis , Scalp , Adenocarcinoma , Endometrial Neoplasms , Neoplasm MetastasisABSTRACT
@#Squamous cell carcinoma is the most common female genital tract malignancy that typically spreads to the pelvic organs first by direct extension, and less commonly to distant sites through lymphangitic and hematogeneous spread. We report on a 47-year-old woman diagnosed with squamous cell carcinoma who underwent concurrent chemoradiation, presenting with a fronto-parietal scalp mass which on histopathologic examination also shows squamous cell carcinoma, likely metastatic.
Subject(s)
Uterine Cervical Neoplasms , Skull , ScalpABSTRACT
Alopecia neoplastica is defined as hair loss secondary to a visceral malignancy that has metastasized to the scalp. The scalp is a relatively common site of cutaneous metastasis, usually presenting as a single or multiple firm scalp nodules. Alopecia neoplastica is a well-recognized but rare presentation, and its pathogenesis is incompletely understood. Atrophy of the hair follicles due to tumor invasion of the scalp plays a role in the development of alopecia. Herein, we describe a 33-year-old woman with gastric adenocarcinoma who developed alopecia neoplastica while receiving cancer chemotherapy. Scalp biopsy revealed metastatic adenocarcinoma cells interspersed between collagen bundles and around hair follicles. Immunohistochemical analysis indicated that the tumor cells originated from the primary gastric adenocarcinoma. Therefore, she was diagnosed with alopecia neoplastica due to gastric adenocarcinoma. The findings from this report may be helpful for understanding the mechanism of alopecia neoplastica.
Subject(s)
Adult , Female , Humans , Adenocarcinoma , Alopecia , Atrophy , Biopsy , Collagen , Drug Therapy , Hair , Hair Follicle , Neoplasm Metastasis , ScalpABSTRACT
Subject(s)
Humans , Adenoids , Carcinoma, Adenoid Cystic , Nasal Cavity , Neoplasm Metastasis , Palate, Hard , Paranasal Sinuses , Recurrence , Salivary Glands , Scalp , Treatment Failure , Treatment OutcomeABSTRACT
We present a case of scalp metastasis from papillary thyroid carcinoma which developed on the scalp of a 57-year-old man. The lesion was noticed at the scalp of left parietal area and a biopsy from the nodule showed mostly metastatic papillary form structures with colloidal structure. We performed immunohistochemistry stain using antithyroglobulin antibody, which established the diagnosis of a metastatic lesion from thyroid papillary carcinoma. Total thyroidectomy, excision of scalp nodule, and 131I radiotherapy were performed. No further metastasis has been discovered during the last 12 months.